Successful emergency transplantation of a liver allograft from a donor maintained on extracorporeal membrane oxygenation.

Journal Article (Journal Article)

The critical shortage of cadaveric donors for organ transplantation has led many transplant centers to accept life-saving organs from donors who would have previously been refused for transplantation. We report a novel case of the use of a liver allograft from a donor whose oxygen delivery was maintained by extracorporeal membrane oxygenation (ECMO) for 29 days before suffering an anoxic brain injury from ECMO dysfunction. Liver transplantation was successfully performed in a patient with fulminant hepatic failure. Immediate graft function was obtained in the recipient, with full neurologic recovery and return to gainful employment 4 months after transplantation. ECMO may provide an intriguing option for the maintenance of organ function in the critically unstable brain-dead organ donor to salvage organs for transplantation. Further studies are currently underway.

Full Text

Duke Authors

Cited Authors

  • Johnson, LB; Plotkin, JS; Howell, CD; Njoku, MJ; Kuo, PC; Bartlett, ST

Published Date

  • March 27, 1997

Published In

Volume / Issue

  • 63 / 6

Start / End Page

  • 910 - 911

PubMed ID

  • 9089236

International Standard Serial Number (ISSN)

  • 0041-1337

Digital Object Identifier (DOI)

  • 10.1097/00007890-199703270-00021


  • eng

Conference Location

  • United States