Half-life analysis of pancreas and kidney transplants.

Published

Journal Article

Although graft and patient survival data are available for pancreas and kidney transplants, they are rarely reported in terms of half-life. Our aim was to determine whether a more relevant measure of outcome is patient and allograft half-life. Using the data from the Organ Procurement and Transplantation Network Registry on kidney and pancreas transplants from January 1988 to December 1996, patient and graft half-life and 95% confidence intervals were calculated and demographic variables compared. No significant differences were found between demographic variables. Kidneys transplanted in diabetics as a simultaneous kidney-pancreas (SPK) fared better than diabetics receiving a kidney alone (9.6 vs. 6.3 years). Pancreatic graft survival in an SPK pair was better than pancreas after kidney transplant or pancreas transplant alone (11.2 vs. 2.5 years). Because kidney and pancreatic grafts have a longer half-life when transplanted with their mate grafts, we should consider the relative benefits of SPKs over pancreas after kidney transplant or pancreas transplant alone to limit the loss of precious resources.

Full Text

Duke Authors

Cited Authors

  • Marroquin, CE; Edwards, EB; Collins, BH; Desai, DM; Tuttle-Newhall, JE; Kuo, PC

Published Date

  • July 2005

Published In

Volume / Issue

  • 80 / 2

Start / End Page

  • 272 - 275

PubMed ID

  • 16041274

Pubmed Central ID

  • 16041274

Electronic International Standard Serial Number (EISSN)

  • 1534-6080

International Standard Serial Number (ISSN)

  • 0041-1337

Digital Object Identifier (DOI)

  • 10.1097/01.tp.0000165094.94020.03

Language

  • eng