The effect of a six-month exercise program on very low-density lipoprotein apolipoprotein B secretion in type 2 diabetes.

Journal Article (Academic Article)

The dyslipidemia and insulin resistance of type 2 diabetes can be improved by aerobic exercise. The effect of 6 months supervised exercise on very low-density lipoprotein (VLDL) apolipoprotein B metabolism was investigated in patients with type 2 diabetes. Moderately obese patients (n = 18) were randomized into supervised (n = 9) and unsupervised (n = 9) exercise groups. All patients were given a training session and a personal exercise program and asked to exercise four times per week at 70% maximal oxygen uptake for 6 months. Patients in the supervised group had a weekly session with an exercise trainer. VLDL apolipoprotein (apo)B metabolism was measured with an infusion of 1-(13)C leucine before and after 6 months of the exercise program. Supervised exercise for 6 months resulted in a significant within-group decrease in percent hemoglobin A1c (P

Duke Authors

Cited Authors

  • Alam, S; Stolinski, M; Pentecost, C; Boroujerdi, MA; Jones, RH; Sonksen, PH; Umpleby, AM

Published Date

  • February 2004

Published In

Volume / Issue

  • 89 / 2

Start / End Page

  • 688 - 694

International Standard Serial Number (ISSN)

  • 0021-972X

Conference Location

  • united states