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Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients.

Publication ,  Journal Article
Cen, YY; Glower, DD; Landolfo, K; Lowe, JE; Davis, RD; Wolfe, WG; Pieper, C; Peterson, B
Published in: J Thorac Cardiovasc Surg
September 2001

OBJECTIVE: We sought to compare 10-year survival in patients after mitral valve replacement with biologic or mechanical valve prostheses. METHODS: Retrospective survival analysis was performed on data from 1139 consecutive patients older than 18 years of age undergoing mitral valve replacement with Carpentier-Edwards (n = 495; Baxter Healthcare Corp, Irvine, Calif) or St Jude Medical (n = 644; St Jude Medical, Inc, St Paul, Minn) prostheses. RESULTS: The 10-year survival was not statistically different between the patients receiving Carpentier-Edwards valves and those receiving St Jude Medical valves (P =.16). Adjusted survival estimates at 2, 5, and 10 years were 82% +/- 2% (95% confidence intervals, 79%-85%), 69% +/- 2% (95% confidence intervals, 64%-73%), and 42% +/- 3% (95% confidence intervals, 37%-48%), respectively, for the Carpentier-Edwards group and 83% +/- 2% (95% confidence intervals, 80%-86%), 72% +/- 2% (95% confidence intervals, 69%-76%), and 51% +/- 3% (95% confidence intervals, 45%-58%), respectively, for the St Jude Medical group. Predictors of worse survival after mitral valve replacement are older age, lower ejection fraction, presence of class IV congestive heart failure, coronary artery disease, renal disease, smoking history, hypertension, concurrent other valve surgery, and redo heart surgery. CONCLUSION: Choice of biologic or mechanical prosthesis does not significantly affect long-term patient survival after mitral valve replacement.

Duke Scholars

Published In

J Thorac Cardiovasc Surg

DOI

ISSN

0022-5223

Publication Date

September 2001

Volume

122

Issue

3

Start / End Page

569 / 577

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Stroke Volume
  • Risk Factors
  • Retrospective Studies
  • Respiratory System
  • Prognosis
  • Predictive Value of Tests
  • Patient Selection
  • Mitral Valve Prolapse
 

Citation

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Cen, Y. Y., Glower, D. D., Landolfo, K., Lowe, J. E., Davis, R. D., Wolfe, W. G., … Peterson, B. (2001). Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients. J Thorac Cardiovasc Surg, 122(3), 569–577. https://doi.org/10.1067/mtc.2001.115418
Cen, Y. Y., D. D. Glower, K. Landolfo, J. E. Lowe, R. D. Davis, W. G. Wolfe, C. Pieper, and B. Peterson. “Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients.J Thorac Cardiovasc Surg 122, no. 3 (September 2001): 569–77. https://doi.org/10.1067/mtc.2001.115418.
Cen YY, Glower DD, Landolfo K, Lowe JE, Davis RD, Wolfe WG, et al. Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients. J Thorac Cardiovasc Surg. 2001 Sep;122(3):569–77.
Cen, Y. Y., et al. “Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients.J Thorac Cardiovasc Surg, vol. 122, no. 3, Sept. 2001, pp. 569–77. Pubmed, doi:10.1067/mtc.2001.115418.
Cen YY, Glower DD, Landolfo K, Lowe JE, Davis RD, Wolfe WG, Pieper C, Peterson B. Comparison of survival after mitral valve replacement with biologic and mechanical valves in 1139 patients. J Thorac Cardiovasc Surg. 2001 Sep;122(3):569–577.
Journal cover image

Published In

J Thorac Cardiovasc Surg

DOI

ISSN

0022-5223

Publication Date

September 2001

Volume

122

Issue

3

Start / End Page

569 / 577

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Survival Analysis
  • Stroke Volume
  • Risk Factors
  • Retrospective Studies
  • Respiratory System
  • Prognosis
  • Predictive Value of Tests
  • Patient Selection
  • Mitral Valve Prolapse