RV functional imaging: 3-D echo-derived dynamic geometry and flow field simulations.

Journal Article (Journal Article)

We describe a novel functional imaging approach for quantitative analysis of right ventricular (RV) blood flow patterns in specific experimental animals (or humans) using real-time, three-dimensional (3-D) echocardiography (RT3D). The method is independent of the digital imaging modality used. It comprises three parts. First, a semiautomated segmentation aided by intraluminal contrast medium locates the RV endocardial surface. Second, a geometric scheme for dynamic RV chamber reconstruction applies a time interpolation procedure to the RT3D data to quantify wall geometry and motion at 400 Hz. A volumetric prism method validated the dynamic geometric reconstruction against simultaneous sonomicrometric canine measurements. Finally, the RV endocardial border motion information is used for mesh generation on a computational fluid dynamics solver to simulate development of the early RV diastolic inflow field. Boundary conditions (tessellated endocardial surface nodal velocities) for the solver are directly derived from the endocardial geometry and motion information. The new functional imaging approach may yield important kinematic information on the distribution of instantaneous velocities in the RV diastolic flow field of specific normal or diseased hearts.

Full Text

Duke Authors

Cited Authors

  • Pasipoularides, AD; Shu, M; Womack, MS; Shah, A; Von Ramm, O; Glower, DD

Published Date

  • January 2003

Published In

Volume / Issue

  • 284 / 1

Start / End Page

  • H56 - H65

PubMed ID

  • 12388220

Pubmed Central ID

  • PMC5789451

International Standard Serial Number (ISSN)

  • 0363-6135

Digital Object Identifier (DOI)

  • 10.1152/ajpheart.00577.2002


  • eng

Conference Location

  • United States