Hemodynamic changes during hemodialysis: role of dialyzate.

Journal Article (Journal Article)

To determine the contribution of the dialyzate to the hemodynamic changes that occur during hemodialysis, echocardiographic measurements obtained during identical conditions of hemodialysis except for the use of different dialyzates were compared. With an acetate-buffer systolic blood pressure and arterial oxygen tension declined but mean rate of left ventricular fiber shortening increased. These changes occurred after only 15 min of hemodialysis. By contrast, with a bicarbonate buffer these alterations did not ensue. Thus, during hemodialysis with limited ultrafiltration, the fall in arterial pressure observed is caused by the acetate-buffer. In hemodynamically unstable patients, bicarbonate may be the preferable dialyzate.

Full Text

Duke Authors

Cited Authors

  • Chen, TS; Friedman, HS; Smith, AJ; Del Monte, ML

Published Date

  • October 1, 1983

Published In

Volume / Issue

  • 20 / 4

Start / End Page

  • 190 - 196

PubMed ID

  • 6641025

International Standard Serial Number (ISSN)

  • 0301-0430


  • eng

Conference Location

  • Germany