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Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas.

Publication ,  Journal Article
Moghrabi, A; Kerby, T; Tien, RD; Friedman, HS
Published in: Pediatr Neurosurg
1995

Brainstem gliomas are an important oncologic problem in the pediatric age group, constituting between 10 and 15% of childhood central nervous system neoplasms. A new classification scheme based on magnetic resonance imaging (MRI) has recently been proposed leading to speculation that gadolinium-DTPA-enhanced MRI may prove useful in defining the prognosis of subsets of patients with these tumors. We retrospectively reviewed gadolinium-DTPA-enhanced MRIs in 26 consecutive newly diagnosed pediatric patients (11 males, 15 females) from our institution between June 1988 and June 1994 with the diagnosis of diffuse brainstem glioma. The site, extent of invasion, T1 and T2 signals, and the pattern and the degree of contrast enhancement of the tumors were evaluated. We correlated the image features, clinical symptoms, and survival period in each patient. Seventeen tumors demonstrated contrast enhancement and 9 did not. The survival in the whole group ranged between 3 months and > 5 years with a median of 9 months. There was no statistical difference in the median survival between patients with or without contrast enhancement (11 versus 8 months).

Duke Scholars

Published In

Pediatr Neurosurg

DOI

ISSN

1016-2291

Publication Date

1995

Volume

23

Issue

6

Start / End Page

293 / 298

Location

Switzerland

Related Subject Headings

  • Survival Rate
  • Prognosis
  • Pentetic Acid
  • Organometallic Compounds
  • Neurology & Neurosurgery
  • Neoplasm Invasiveness
  • Male
  • Magnetic Resonance Imaging
  • Infant
  • Humans
 

Citation

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ICMJE
MLA
NLM
Moghrabi, A., Kerby, T., Tien, R. D., & Friedman, H. S. (1995). Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. Pediatr Neurosurg, 23(6), 293–298. https://doi.org/10.1159/000120974
Moghrabi, A., T. Kerby, R. D. Tien, and H. S. Friedman. “Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas.Pediatr Neurosurg 23, no. 6 (1995): 293–98. https://doi.org/10.1159/000120974.
Moghrabi A, Kerby T, Tien RD, Friedman HS. Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. Pediatr Neurosurg. 1995;23(6):293–8.
Moghrabi, A., et al. “Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas.Pediatr Neurosurg, vol. 23, no. 6, 1995, pp. 293–98. Pubmed, doi:10.1159/000120974.
Moghrabi A, Kerby T, Tien RD, Friedman HS. Prognostic value of contrast-enhanced magnetic resonance imaging in brainstem gliomas. Pediatr Neurosurg. 1995;23(6):293–298.
Journal cover image

Published In

Pediatr Neurosurg

DOI

ISSN

1016-2291

Publication Date

1995

Volume

23

Issue

6

Start / End Page

293 / 298

Location

Switzerland

Related Subject Headings

  • Survival Rate
  • Prognosis
  • Pentetic Acid
  • Organometallic Compounds
  • Neurology & Neurosurgery
  • Neoplasm Invasiveness
  • Male
  • Magnetic Resonance Imaging
  • Infant
  • Humans