Transient late magnetic resonance imaging changes suggesting progression of brain stem glioma: implications for entry criteria for phase II trials.

Journal Article

An 8-year-old boy was treated with irradiation (66 Gy) for a brain stem glioma. Five months after the completion of radiotherapy, magnetic resonance imaging demonstrated apparent tumor progression despite the patient's neurological improvement. The child continued to improve, with subsequent radiographic evidence of tumor regression, without additional therapeutic intervention. The evaluations of response and recurrence of brain tumors as well as entry criteria for Phase II studies are discussed.

Full Text

Duke Authors

Cited Authors

  • Longee, DC; Friedman, HS; Djang, WT; Halperin, E; Schold, SC; Oakes, WJ

Published Date

  • August 1988

Published In

Volume / Issue

  • 23 / 2

Start / End Page

  • 248 - 253

PubMed ID

  • 3054620

Pubmed Central ID

  • 3054620

International Standard Serial Number (ISSN)

  • 0148-396X

Digital Object Identifier (DOI)

  • 10.1227/00006123-198808000-00024


  • eng

Conference Location

  • United States