Treatment of platelet alloimmunization with intravenous immunoglobulin. Two case reports and review of the literature.

Journal Article (Journal Article)

Two pediatric patients with severe aplastic anemia, elevated antiplatelet antibody levels, refractoriness to human lymphocyte antigen-matched platelet transfusions, and sustained bleeding problems were treated with intravenous immunoglobulin (IVIG), pH 4.25, for three to over nine months. Improved responses to platelet infusions and improved hemostasis were demonstrated in both patients. A review of the published literature analyzing the role of IVIG in the treatment of platelet alloimmunization is presented.

Full Text

Duke Authors

Cited Authors

  • Kurtzberg, J; Friedman, HS; Kinney, TR; Chaffee, S; Falletta, JM

Published Date

  • October 23, 1987

Published In

Volume / Issue

  • 83 / 4A

Start / End Page

  • 30 - 33

PubMed ID

  • 3118706

International Standard Serial Number (ISSN)

  • 0002-9343

Digital Object Identifier (DOI)

  • 10.1016/0002-9343(87)90548-1


  • eng

Conference Location

  • United States