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Osteoblastic metastases from astrocytomas: a report of two cases.

Publication ,  Journal Article
Longee, DC; Friedman, HS; Phillips, PC; Burger, PC; Oakes, WJ; Heffez, D; Wharam, M; Strauss, L; Fuller, GN; Schold, SC
Published in: Med Pediatr Oncol
1991

The spread of primary central nervous system (CNS) neoplasms beyond the confines of the neuraxis is a relatively uncommon observation. Extraneural metastases involving bone are quite rare, and have been observed almost exclusively in cases of medulloblastoma, high-grade (III-IV) astrocytoma, and glioblastoma multiforme. To date there has been only one case reported of bone metastasis from a "well-differentiated" astrocytoma. We now report two cases of astrocytoma in children with diffuse osteoblastic metastases and a fulminant clinical course. These cases demonstrate that due to the potential morphologic heterogeneity of these neoplasms, an initial biopsy diagnosis of low-grade astrocytoma does not always imply a benign clinical course.

Duke Scholars

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1991

Volume

19

Issue

4

Start / End Page

318 / 324

Location

United States

Related Subject Headings

  • Spinal Cord Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Humans
  • Female
  • Child
  • Brain Neoplasms
  • Bone Neoplasms
  • Astrocytoma
  • Adolescent
 

Citation

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ICMJE
MLA
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Longee, D. C., Friedman, H. S., Phillips, P. C., Burger, P. C., Oakes, W. J., Heffez, D., … Schold, S. C. (1991). Osteoblastic metastases from astrocytomas: a report of two cases. Med Pediatr Oncol, 19(4), 318–324. https://doi.org/10.1002/mpo.2950190419
Longee, D. C., H. S. Friedman, P. C. Phillips, P. C. Burger, W. J. Oakes, D. Heffez, M. Wharam, L. Strauss, G. N. Fuller, and S. C. Schold. “Osteoblastic metastases from astrocytomas: a report of two cases.Med Pediatr Oncol 19, no. 4 (1991): 318–24. https://doi.org/10.1002/mpo.2950190419.
Longee DC, Friedman HS, Phillips PC, Burger PC, Oakes WJ, Heffez D, et al. Osteoblastic metastases from astrocytomas: a report of two cases. Med Pediatr Oncol. 1991;19(4):318–24.
Longee, D. C., et al. “Osteoblastic metastases from astrocytomas: a report of two cases.Med Pediatr Oncol, vol. 19, no. 4, 1991, pp. 318–24. Pubmed, doi:10.1002/mpo.2950190419.
Longee DC, Friedman HS, Phillips PC, Burger PC, Oakes WJ, Heffez D, Wharam M, Strauss L, Fuller GN, Schold SC. Osteoblastic metastases from astrocytomas: a report of two cases. Med Pediatr Oncol. 1991;19(4):318–324.

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1991

Volume

19

Issue

4

Start / End Page

318 / 324

Location

United States

Related Subject Headings

  • Spinal Cord Neoplasms
  • Oncology & Carcinogenesis
  • Male
  • Humans
  • Female
  • Child
  • Brain Neoplasms
  • Bone Neoplasms
  • Astrocytoma
  • Adolescent