Skip to main content

False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors.

Publication ,  Journal Article
Nelson, SC; Friedman, HS; Hockenberger, B; Vandersteenhoven, JJ; Gray, L; Touri, SL; Oakes, WJ
Published in: Med Pediatr Oncol
1993

Gadolinium-DTPA enhanced MRI is the modality of choice when imaging central nervous system infratentorial tumors in the pediatric population. The detection of a new enhancing lesion following initiation of therapy is typically considered pathognomonic for recurrent or metastatic tumor. We report two pediatric patients with infratentorial central nervous system tumors who demonstrated new areas of enhancement with gadolinium-DTPA enhanced MRI following initiation of multimodality therapy. Both patients had surgical biopsy of the new lesions with histologic review failing to demonstrate viable tumor. These studies suggest caution in considering new enhancing lesions detected by MRI in a child with a brain tumor pathognomonic for new sites of active tumor.

Duke Scholars

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1993

Volume

21

Issue

5

Start / End Page

350 / 355

Location

United States

Related Subject Headings

  • Pentetic Acid
  • Organometallic Compounds
  • Oncology & Carcinogenesis
  • Neoplasm Recurrence, Local
  • Magnetic Resonance Imaging
  • Infratentorial Neoplasms
  • Humans
  • Gadolinium DTPA
  • Female
  • False Positive Reactions
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nelson, S. C., Friedman, H. S., Hockenberger, B., Vandersteenhoven, J. J., Gray, L., Touri, S. L., & Oakes, W. J. (1993). False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors. Med Pediatr Oncol, 21(5), 350–355. https://doi.org/10.1002/mpo.2950210508
Nelson, S. C., H. S. Friedman, B. Hockenberger, J. J. Vandersteenhoven, L. Gray, S. L. Touri, and W. J. Oakes. “False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors.Med Pediatr Oncol 21, no. 5 (1993): 350–55. https://doi.org/10.1002/mpo.2950210508.
Nelson SC, Friedman HS, Hockenberger B, Vandersteenhoven JJ, Gray L, Touri SL, et al. False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors. Med Pediatr Oncol. 1993;21(5):350–5.
Nelson, S. C., et al. “False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors.Med Pediatr Oncol, vol. 21, no. 5, 1993, pp. 350–55. Pubmed, doi:10.1002/mpo.2950210508.
Nelson SC, Friedman HS, Hockenberger B, Vandersteenhoven JJ, Gray L, Touri SL, Oakes WJ. False-positive MRI detection of recurrent or metastatic pediatric infratentorial tumors. Med Pediatr Oncol. 1993;21(5):350–355.

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1993

Volume

21

Issue

5

Start / End Page

350 / 355

Location

United States

Related Subject Headings

  • Pentetic Acid
  • Organometallic Compounds
  • Oncology & Carcinogenesis
  • Neoplasm Recurrence, Local
  • Magnetic Resonance Imaging
  • Infratentorial Neoplasms
  • Humans
  • Gadolinium DTPA
  • Female
  • False Positive Reactions