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Microcirculatory responses to vascular washout following ischemia.

Publication ,  Journal Article
Howell, ST; Seaber, AV; Urbaniak, JR
Published in: Microsurgery
1989

This study examined the microcirculatory alterations in the hindlimb of the rat caused by ischemia and vascular washout with lactated Ringer's solution. Experimental groups consisted of innervated and denervated animals, each subjected to 2 hours of hindlimb ischemia. The ischemic period was then followed by either vascular washout or no washout prior to reperfusion. The cutaneous capillary blood flow was measured using laser Doppler velocimetry. The results demonstrated a substantial increase in early reperfusion flow above baseline in the innervated groups, more apparent in the group subjected to vascular washout. In all cases where there was elevated early flow, later flow levels were decreased. The results and proposed mechanisms of the response are discussed.

Duke Scholars

Published In

Microsurgery

DOI

ISSN

0738-1085

Publication Date

1989

Volume

10

Issue

4

Start / End Page

264 / 268

Location

United States

Related Subject Headings

  • Surgical Flaps
  • Surgery
  • Skin
  • Rats, Inbred Strains
  • Rats
  • Microcirculation
  • Ischemia
  • Denervation
  • Blood Pressure
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Howell, S. T., Seaber, A. V., & Urbaniak, J. R. (1989). Microcirculatory responses to vascular washout following ischemia. Microsurgery, 10(4), 264–268. https://doi.org/10.1002/micr.1920100403
Howell, S. T., A. V. Seaber, and J. R. Urbaniak. “Microcirculatory responses to vascular washout following ischemia.Microsurgery 10, no. 4 (1989): 264–68. https://doi.org/10.1002/micr.1920100403.
Howell ST, Seaber AV, Urbaniak JR. Microcirculatory responses to vascular washout following ischemia. Microsurgery. 1989;10(4):264–8.
Howell, S. T., et al. “Microcirculatory responses to vascular washout following ischemia.Microsurgery, vol. 10, no. 4, 1989, pp. 264–68. Pubmed, doi:10.1002/micr.1920100403.
Howell ST, Seaber AV, Urbaniak JR. Microcirculatory responses to vascular washout following ischemia. Microsurgery. 1989;10(4):264–268.
Journal cover image

Published In

Microsurgery

DOI

ISSN

0738-1085

Publication Date

1989

Volume

10

Issue

4

Start / End Page

264 / 268

Location

United States

Related Subject Headings

  • Surgical Flaps
  • Surgery
  • Skin
  • Rats, Inbred Strains
  • Rats
  • Microcirculation
  • Ischemia
  • Denervation
  • Blood Pressure
  • Animals