Inhibition of epinephrine-induced vasospasm with adrenoreceptor blockade in the rat cremaster muscle.

Published

Journal Article

This study demonstrates that intravenous epinephrine causes arterial vasospasm, but not venous constriction, in the microcirculation of the rat cremaster muscle. This effect can be blocked by a smooth muscle relaxant such as papaverine or an alpha receptor antagonist such as phentolamine. Circulating vasospastic agents such as epinephrine are important determinants of microcirculatory blood flow, and inhibition by pharmacologic means may enhance blood flow and survival in microvascular surgery.

Full Text

Pubmed Central version
Link to Item

Duke Authors

Urbaniak, James Randolph

Cited Authors

Hartsock, LA; Seaber, AV; Urbaniak, JR

Published Date

1991

Published In

Microsurgery

Volume / Issue

12 / 1

Start / End Page

55 - 59

PubMed ID

1990250

Pubmed Central ID

1990250

International Standard Serial Number (ISSN)

0738-1085

Language

Conference Location

United States