Adipose-derived adult stem cells: isolation, characterization, and differentiation potential.

Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S., Review

Adipose tissue is an abundant, accessible, and replenishable source of adult stem cells that can be isolated from liposuction waste tissue by collagenase digestion and differential centrifugation. These adipose-derived adult stem (ADAS) cells are multipotent, differentiating along the adipocyte, chondrocyte, myocyte, neuronal, and osteoblast lineages, and can serve in other capacities, such as providing hematopoietic support and gene transfer. ADAS cells have potential applications for the repair and regeneration of acute and chronically damaged tissues. Additional pre-clinical safety and efficacy studies will be needed before the promise of these cells can be fully realized.

Full Text

Duke Authors

Cited Authors

  • Gimble, J; Guilak, F

Published Date

  • 2003

Published In

Volume / Issue

  • 5 / 5

Start / End Page

  • 362 - 369

PubMed ID

  • 14578098

International Standard Serial Number (ISSN)

  • 1465-3249

Digital Object Identifier (DOI)

  • 10.1080/14653240310003026

Language

  • eng

Citation Source

  • PubMed