Right ventricular free wall isolation: effects on regional myocardial blood flow.

Journal Article (Journal Article)

The right ventricular isolation procedure was developed to treat medically refractory, nonischemic right ventricular tachycardia. The effect of this procedure on regional myocardial blood flow to the isolated right ventricle was evaluated in 10 adult mongrel dogs. There were no significant changes in aortic pressure, right ventricular systolic or diastolic pressure, or cardiac index following right ventricular isolation when the left ventricle and right ventricular free wall were synchronously paced. Myocardial blood flow to the isolated right ventricle was unchanged following the procedure (0.85 +/- 0.07 ml/min/gm to 0.87 +/- 0.08 ml/min/gm; p = not significant). Analysis of regional flow revealed that only a thin rim of right ventricular tissue near the ventriculotomy showed a significant decrease in blood flow (1.10 +/- 0.1 ml/min/gm to 0.29 +/- 0.04 ml/min/gm; p less than 0.05). Thus, this procedure leaves intact the blood supply to the great percentage of the right ventricular free wall. This finding supports the concept that the right ventricular isolation procedure is effective in isolating abnormal electrical activity without compromising regional myocardial blood flow.

Full Text

Duke Authors

Cited Authors

  • Damiano, RJ; Asano, T; Smith, PK; Ferguson, TB; Cox, JL

Published Date

  • October 1988

Published In

Volume / Issue

  • 46 / 4

Start / End Page

  • 391 - 395

PubMed ID

  • 3178347

International Standard Serial Number (ISSN)

  • 0003-4975

Digital Object Identifier (DOI)

  • 10.1016/s0003-4975(10)64650-4


  • eng

Conference Location

  • Netherlands