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Right ventricular free wall isolation: effects on regional myocardial blood flow.

Publication ,  Journal Article
Damiano, RJ; Asano, T; Smith, PK; Ferguson, TB; Cox, JL
Published in: Ann Thorac Surg
October 1988

The right ventricular isolation procedure was developed to treat medically refractory, nonischemic right ventricular tachycardia. The effect of this procedure on regional myocardial blood flow to the isolated right ventricle was evaluated in 10 adult mongrel dogs. There were no significant changes in aortic pressure, right ventricular systolic or diastolic pressure, or cardiac index following right ventricular isolation when the left ventricle and right ventricular free wall were synchronously paced. Myocardial blood flow to the isolated right ventricle was unchanged following the procedure (0.85 +/- 0.07 ml/min/gm to 0.87 +/- 0.08 ml/min/gm; p = not significant). Analysis of regional flow revealed that only a thin rim of right ventricular tissue near the ventriculotomy showed a significant decrease in blood flow (1.10 +/- 0.1 ml/min/gm to 0.29 +/- 0.04 ml/min/gm; p less than 0.05). Thus, this procedure leaves intact the blood supply to the great percentage of the right ventricular free wall. This finding supports the concept that the right ventricular isolation procedure is effective in isolating abnormal electrical activity without compromising regional myocardial blood flow.

Duke Scholars

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

October 1988

Volume

46

Issue

4

Start / End Page

391 / 395

Location

Netherlands

Related Subject Headings

  • Tachycardia
  • Respiratory System
  • Heart Ventricles
  • Dogs
  • Coronary Circulation
  • Cardiac Surgical Procedures
  • Animals
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
 

Citation

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Damiano, R. J., Asano, T., Smith, P. K., Ferguson, T. B., & Cox, J. L. (1988). Right ventricular free wall isolation: effects on regional myocardial blood flow. Ann Thorac Surg, 46(4), 391–395. https://doi.org/10.1016/s0003-4975(10)64650-4
Damiano, R. J., T. Asano, P. K. Smith, T. B. Ferguson, and J. L. Cox. “Right ventricular free wall isolation: effects on regional myocardial blood flow.Ann Thorac Surg 46, no. 4 (October 1988): 391–95. https://doi.org/10.1016/s0003-4975(10)64650-4.
Damiano RJ, Asano T, Smith PK, Ferguson TB, Cox JL. Right ventricular free wall isolation: effects on regional myocardial blood flow. Ann Thorac Surg. 1988 Oct;46(4):391–5.
Damiano, R. J., et al. “Right ventricular free wall isolation: effects on regional myocardial blood flow.Ann Thorac Surg, vol. 46, no. 4, Oct. 1988, pp. 391–95. Pubmed, doi:10.1016/s0003-4975(10)64650-4.
Damiano RJ, Asano T, Smith PK, Ferguson TB, Cox JL. Right ventricular free wall isolation: effects on regional myocardial blood flow. Ann Thorac Surg. 1988 Oct;46(4):391–395.
Journal cover image

Published In

Ann Thorac Surg

DOI

ISSN

0003-4975

Publication Date

October 1988

Volume

46

Issue

4

Start / End Page

391 / 395

Location

Netherlands

Related Subject Headings

  • Tachycardia
  • Respiratory System
  • Heart Ventricles
  • Dogs
  • Coronary Circulation
  • Cardiac Surgical Procedures
  • Animals
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences