Emerging clinical applications of RNA.

Journal Article (Review)

RNA is a versatile biological macromolecule that is crucial in mobilizing and interpreting our genetic information. It is not surprising then that researchers have sought to exploit the inherent properties of RNAs so as to interfere with or repair dysfunctional nucleic acids or proteins and to stimulate the production of therapeutic gene products in a variety of pathological situations. The first generation of the resulting RNA therapeutics are now being evaluated in clinical trials, raising significant interest in this emerging area of medical research.

Full Text

Duke Authors

Cited Authors

  • Sullenger, BA; Gilboa, E

Published Date

  • July 11, 2002

Published In

Volume / Issue

  • 418 / 6894

Start / End Page

  • 252 - 258

PubMed ID

  • 12110902

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/418252a

Language

  • eng

Conference Location

  • England