Revising messages traveling along the cellular information superhighway.

Journal Article (Journal Article;Review)

Cells use RNA messages to carry instructions from the genome to ribosomes about the types of proteins that should be made. These messages are generally revised by splicing before translation. Engineering ribozymes that can use splicing to repair mutant transcripts may be a useful approach to gene therapy of several genetic diseases.

Full Text

Duke Authors

Cited Authors

  • Sullenger, BA

Published Date

  • May 1995

Published In

Volume / Issue

  • 2 / 5

Start / End Page

  • 249 - 253

PubMed ID

  • 9383426

International Standard Serial Number (ISSN)

  • 1074-5521

Digital Object Identifier (DOI)

  • 10.1016/1074-5521(95)90043-8


  • eng

Conference Location

  • United States