Paroxysmal cold hemoglobinuria and cardiopulmonary bypass.

Journal Article (Journal Article)

Paroxysmal cold hemoglobinuria, a cold-reactive autoimmune disease associated with the Donath-Landsteiner antibody, has not been described in patients undergoing cardiac surgery. We report a case of mitral valve replacement in a woman with a positive Donath-Landsteiner antibody and a history of recurrent hemolysis and hemoglobinuria secondary to cold exposure. Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.

Full Text

Duke Authors

Cited Authors

  • Kypson, AP; Warner, JJ; Telen, MJ; Milano, CA

Published Date

  • February 2003

Published In

Volume / Issue

  • 75 / 2

Start / End Page

  • 579 - 581

PubMed ID

  • 12607681

International Standard Serial Number (ISSN)

  • 0003-4975

Digital Object Identifier (DOI)

  • 10.1016/s0003-4975(02)04337-0


  • eng

Conference Location

  • Netherlands