Erythrocyte Webb-type glycophorin C variant lacks N-glycosylation due to an asparagine to serine substitution.

Published

Journal Article

We have analyzed part of the sequence of the human glycophorin C (GPC) gene carried by a Webb blood-group positive donor. Our results indicate that the lack of N-glycosylation of the variant GPC associated with the Webb phenotype is due to a point mutation resulting in an asparagine to serine substitution at amino acid position 8.