DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy.
Publication
, Journal Article
Robertson, CN; Paulson, DF
Published in: Acta Oncol
1991
In a series of 94 patients with prostatic adenocarcinoma the prognostic significance of some factors was studied after radical prostatectomy. DNA ploidy was assessed by flow cytometry of cells from deparaffinized specimens. Gleason sum, seminal vesicle status and ploidy turned all out to be important predictors of disease progression. The ploidy status significantly enhanced the ability to prognostically evaluate patients with intermediate grade carcinoma compared to tumor grade alone. Patients with seminal vesicle invasion and aneuploidy had a very poor prognosis which prompts trials with alternatives of adjuvant therapy in this patient population.
Duke Scholars
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Published In
Acta Oncol
DOI
ISSN
0284-186X
Publication Date
1991
Volume
30
Issue
2
Start / End Page
205 / 207
Location
Sweden
Related Subject Headings
- Seminal Vesicles
- Prostatic Neoplasms
- Prostatectomy
- Prognosis
- Ploidies
- Oncology & Carcinogenesis
- Neoplasm Staging
- Male
- Humans
- Flow Cytometry
Citation
APA
Chicago
ICMJE
MLA
NLM
Robertson, C. N., & Paulson, D. F. (1991). DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy. Acta Oncol, 30(2), 205–207. https://doi.org/10.3109/02841869109092351
Robertson, C. N., and D. F. Paulson. “DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy.” Acta Oncol 30, no. 2 (1991): 205–7. https://doi.org/10.3109/02841869109092351.
Robertson CN, Paulson DF. DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy. Acta Oncol. 1991;30(2):205–7.
Robertson, C. N., and D. F. Paulson. “DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy.” Acta Oncol, vol. 30, no. 2, 1991, pp. 205–07. Pubmed, doi:10.3109/02841869109092351.
Robertson CN, Paulson DF. DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy. Acta Oncol. 1991;30(2):205–207.
Published In
Acta Oncol
DOI
ISSN
0284-186X
Publication Date
1991
Volume
30
Issue
2
Start / End Page
205 / 207
Location
Sweden
Related Subject Headings
- Seminal Vesicles
- Prostatic Neoplasms
- Prostatectomy
- Prognosis
- Ploidies
- Oncology & Carcinogenesis
- Neoplasm Staging
- Male
- Humans
- Flow Cytometry