CD20: a regulator of cell-cycle progression of B lymphocytes.
CD20 is a B-cell-specific cell-surface molecule with four membrane-spanning domains, as well as cytoplasmic N- and C-terminal domains. Here, Thomas Tedder and Pablo Engel discuss the suggestion that CD20 is a regulator of transmembrane Ca2+ conductance and plays an important functional role in B-cell activation, proliferation and differentiation.
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