CD molecules 2005: human cell differentiation molecules.


Journal Article

The immune system works through leukocytes interacting with each other, with other cells, with tissue matrices, with infectious agents, and with other antigens. These interactions are mediated by cell-surface glycoproteins and glycolipids. Antibodies against these leukocyte molecules have provided powerful tools for analysis of their structure, function, and distribution. Antibodies have been used widely in hematology, immunology, and pathology, and in research, diagnosis, and therapy. The associated CD nomenclature is commonly used when referring to leukocyte surface molecules and antibodies against them. It provides an essential classification for diagnostic and therapeutic purposes. The most recent (8th) Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Adelaide, Australia, in December 2004, allocated 95 new CD designations and made radical changes to its aims and future operational strategy in order to maintain its relevance to modern human biology and clinical practice.

Full Text

Duke Authors

Cited Authors

  • Zola, H; Swart, B; Nicholson, I; Aasted, B; Bensussan, A; Boumsell, L; Buckley, C; Clark, G; Drbal, K; Engel, P; Hart, D; Horejsí, V; Isacke, C; Macardle, P; Malavasi, F; Mason, D; Olive, D; Saalmueller, A; Schlossman, SF; Schwartz-Albiez, R; Simmons, P; Tedder, TF; Uguccioni, M; Warren, H

Published Date

  • November 1, 2005

Published In

Volume / Issue

  • 106 / 9

Start / End Page

  • 3123 - 3126

PubMed ID

  • 16020511

Pubmed Central ID

  • 16020511

International Standard Serial Number (ISSN)

  • 0006-4971

Digital Object Identifier (DOI)

  • 10.1182/blood-2005-03-1338


  • eng

Conference Location

  • United States