An experimental model of ectropion uveae and iris neovascularization in the cat.

Journal Article (Journal Article)

Neovascularization of the iris (NVI) is one of the most frequently studied intraocular vascular proliferations in animal models. Ectropion uveae has not been a consistent finding in these studies. In this study, a surgical model of ectropion uveae and iris neovascularization was developed that involved lensectomy, vitrectomy, bipolar cautery and transection of all three principal branch veins in the cat eye. Twelve of 14 eyes that received this procedure developed postoperative retinal detachments with a clinical picture of hemorrhagic retinopathy. These eyes progressed to a clinical picture of NVI within 1-7 wk. Eight eyes developed ectropion uveae for as much as 300 degrees. At the light microscopic level, a fibrovascular membrane was apparent on the anterior iris stroma in 9 of 14 eyes and further involved the angle in six eyes.

Full Text

Duke Authors

Cited Authors

  • Hjelmeland, LM; Stewart, MW; Li, J; Toth, CA; Burns, MS; Landers, MB

Published Date

  • April 1992

Published In

Volume / Issue

  • 33 / 5

Start / End Page

  • 1796 - 1803

PubMed ID

  • 1373124

International Standard Serial Number (ISSN)

  • 0146-0404


  • eng

Conference Location

  • United States