Procoagulant effects of intraocular sodium hyaluronate (Healon) after phakic diabetic vitrectomy. A prospective, randomized study.

Journal Article (Clinical Trial;Journal Article;Multicenter Study)

A procoagulant effect was reported previously after injection of 0.50 to 0.75 ml of sodium hyaluronate (Healon) into the vitreous cavity at the end of phakic diabetic vitrectomies. A multicenter, randomized, prospective trial was done to study this effect. In the treatment group the media was clear in 50% of eyes in the immediate postoperative period compared with only 8% in the control group. At 2 to 6 weeks, there was no statistically significant difference between the two groups. The authors conclude that such sodium hyaluronate injection provides clear media in a significant number of eyes in the immediate postoperative period, potentially allowing thorough postoperative evaluation and early retinal photocoagulation if needed.

Full Text

Duke Authors

Cited Authors

  • Packer, AJ; McCuen, BW; Hutton, WL; Ramsay, RC

Published Date

  • October 1989

Published In

Volume / Issue

  • 96 / 10

Start / End Page

  • 1491 - 1494

PubMed ID

  • 2685709

International Standard Serial Number (ISSN)

  • 0161-6420

Digital Object Identifier (DOI)

  • 10.1016/s0161-6420(89)32686-8


  • eng

Conference Location

  • United States