Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96.

Journal Article (Journal Article;Review)

The past year has born witness to compelling demonstrations of the utility of peptide complexes with glucose regulated protein 94 (GRP94, also known as gp96) in cancer immunotherapy. Insights into the structural basis of peptide binding to GRP94 have been obtained and the role of the transporter for antigen presentation in defining the GRP94-bound peptide composition has been determined.

Full Text

Duke Authors

Cited Authors

  • Nicchitta, CV

Published Date

  • February 1998

Published In

Volume / Issue

  • 10 / 1

Start / End Page

  • 103 - 109

PubMed ID

  • 9523119

International Standard Serial Number (ISSN)

  • 0952-7915

Digital Object Identifier (DOI)

  • 10.1016/s0952-7915(98)80039-3


  • eng

Conference Location

  • England