Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression.

Journal Article (Journal Article)

CD1d, a nonclassical MHC class I-like molecule, is prominently expressed on intestinal epithelial cells and is thought to function in the regulation of intestinal intraepithelial lymphocyte activity. Hsp110, an abundant heat shock protein present in essentially all mammalian tissues, has now been shown to upregulate CD1d expression in colonic tissue culture cell lines. Might this abundant chaperone serve an autocrine function in the regulation of CD1d expression?

Full Text

Duke Authors

Cited Authors

  • Nicchitta, CV

Published Date

  • September 2003

Published In

Volume / Issue

  • 112 / 5

Start / End Page

  • 646 - 648

PubMed ID

  • 12952910

Pubmed Central ID

  • PMC182217

International Standard Serial Number (ISSN)

  • 0021-9738

Digital Object Identifier (DOI)

  • 10.1172/JCI19641

Language

  • eng

Conference Location

  • United States