Come forth CD1d: Hsp110 in the regulation of intestinal epithelial CD1d expression.
Journal Article (Journal Article)
CD1d, a nonclassical MHC class I-like molecule, is prominently expressed on intestinal epithelial cells and is thought to function in the regulation of intestinal intraepithelial lymphocyte activity. Hsp110, an abundant heat shock protein present in essentially all mammalian tissues, has now been shown to upregulate CD1d expression in colonic tissue culture cell lines. Might this abundant chaperone serve an autocrine function in the regulation of CD1d expression?
Full Text
Duke Authors
Cited Authors
- Nicchitta, CV
Published Date
- September 2003
Published In
Volume / Issue
- 112 / 5
Start / End Page
- 646 - 648
PubMed ID
- 12952910
Pubmed Central ID
- PMC182217
International Standard Serial Number (ISSN)
- 0021-9738
Digital Object Identifier (DOI)
- 10.1172/JCI19641
Language
- eng
Conference Location
- United States