Exclusion of identified LGMD1 loci from four dominant limb-girdle muscular dystrophy families.

Journal Article (Journal Article)

The limb-girdle muscular dystrophies are a clinically and genetically heterogeneous group of disorders. Recent linkage analyses and positional cloning studies have identified numerous loci responsible for the recessive and dominant forms, underscoring the inherent heterogeneity. In this report, we investigate four large autosomal dominant limb-girdle pedigrees and exclude these pedigrees from linkage to these loci. In addition, there is no evidence for linkage to any of the seven recessive LGMD loci.

Full Text

Duke Authors

Cited Authors

  • Speer, MC; Vance, JM; Lennon-Graham, F; Stajich, JM; Viles, KD; Gilchrist, JM; Nigro, V; McMichael, R; Chutkow, JG; Bartoloni, L; Horrigan, SK; Westbrook, CA; Pericak-Vance, MA

Published Date

  • July 1998

Published In

Volume / Issue

  • 48 / 4

Start / End Page

  • 179 - 184

PubMed ID

  • 9694248

Pubmed Central ID

  • 9694248

International Standard Serial Number (ISSN)

  • 0001-5652

Digital Object Identifier (DOI)

  • 10.1159/000022799

Language

  • eng

Conference Location

  • Switzerland