Exclusion of identified LGMD1 loci from four dominant limb-girdle muscular dystrophy families.
Published
Journal Article
The limb-girdle muscular dystrophies are a clinically and genetically heterogeneous group of disorders. Recent linkage analyses and positional cloning studies have identified numerous loci responsible for the recessive and dominant forms, underscoring the inherent heterogeneity. In this report, we investigate four large autosomal dominant limb-girdle pedigrees and exclude these pedigrees from linkage to these loci. In addition, there is no evidence for linkage to any of the seven recessive LGMD loci.
Full Text
Duke Authors
Cited Authors
- Speer, MC; Vance, JM; Lennon-Graham, F; Stajich, JM; Viles, KD; Gilchrist, JM; Nigro, V; McMichael, R; Chutkow, JG; Bartoloni, L; Horrigan, SK; Westbrook, CA; Pericak-Vance, MA
Published Date
- July 1998
Published In
Volume / Issue
- 48 / 4
Start / End Page
- 179 - 184
PubMed ID
- 9694248
Pubmed Central ID
- 9694248
International Standard Serial Number (ISSN)
- 0001-5652
Digital Object Identifier (DOI)
- 10.1159/000022799
Language
- eng
Conference Location
- Switzerland