Heterogeneity in Paget disease of the bone.

Journal Article (Journal Article)

Paget disease of the bone is a common skeletal disorder. Recently, a gene for Paget disease was localized to 18q with subsequent evidence for linkage heterogeneity. We report the identification and clinical characterization of a large pedigree of Paget disease and demonstrate that the Paget disease gene in this pedigree is not linked to the region on 18q, thus confirming linkage heterogeneity.

Full Text

Duke Authors

Cited Authors

  • Nance, MA; Nuttall, FQ; Econs, MJ; Lyles, KW; Viles, KD; Vance, JM; Pericak-Vance, MA; Speer, MC

Published Date

  • June 19, 2000

Published In

Volume / Issue

  • 92 / 5

Start / End Page

  • 303 - 307

PubMed ID

  • 10861657

International Standard Serial Number (ISSN)

  • 0148-7299

Digital Object Identifier (DOI)

  • 10.1002/1096-8628(20000619)92:5<303::aid-ajmg2>3.0.co;2-e


  • eng

Conference Location

  • United States