North Carolina macular dystrophy: exclusion map using RFLPs and microsatellites.

Journal Article (Journal Article)

The autosomal dominant macular dystrophies are a confusing group of poorly understood diseases. Linkage studies will greatly aid our classification of these disorders and hopefully provide insight into central retinal function and dysfunction such as occurs in age-related macular degeneration. North Carolina macular dystrophy is one such disease that has been amenable to linkage analysis because of the large pedigree size. Seventy-six polymorphic markers have been tested for linkage and exclusion data are presented.

Full Text

Duke Authors

Cited Authors

  • Small, KW; Weber, JL; Hung, WY; Vance, J; Roses, A; Pericak-Vance, M

Published Date

  • November 1991

Published In

Volume / Issue

  • 11 / 3

Start / End Page

  • 763 - 766

PubMed ID

  • 1685483

International Standard Serial Number (ISSN)

  • 0888-7543

Digital Object Identifier (DOI)

  • 10.1016/0888-7543(91)90087-u


  • eng

Conference Location

  • United States