A statistic for comparing two correlated markers which are prognostic for time to an event.

Journal Article (Journal Article)

A proliferation of biologic markers has led to increased interest in methods for comparing the prognostic value of markers in predicting time to recurrence of or death from disease. This paper proposes a nonparametric test statistic for comparing two continuous markers when the outcome of interest is time to an event and the outcome is subject to right censoring. Results from Monte Carlo studies show that the new testing procedure is reliable for practical use. We present an example in which we use the statistic successfully in a colon cancer study to select between two potentially useful markers.

Full Text

Duke Authors

Cited Authors

  • Jung, SH; Wieand, S; Cha, SS

Published Date

  • October 30, 1995

Published In

Volume / Issue

  • 14 / 20

Start / End Page

  • 2217 - 2225

PubMed ID

  • 8552898

International Standard Serial Number (ISSN)

  • 0277-6715

Digital Object Identifier (DOI)

  • 10.1002/sim.4780142005


  • eng

Conference Location

  • England