A phase II study of paclitaxel and granulocyte colony-stimulating factor in previously untreated patients with extensive-stage small cell lung cancer: a study of the North Central Cancer Treatment Group.

Published

Journal Article

In 1994, approximately 34,000 to 43,000 Americans will be diagnosed with small cell lung cancer, and 60% to 70% of these individuals will have extensive-stage disease. The median survival time of patients with extensive-stage small cell lung cancer is 8 to 10 months and 10% or less will survive 2 years. There have been no major advances in the treatment of this stage of disease in the past decade. Phase II trials with promising new single-agent chemotherapeutic drugs are justifiable. We report the design and toxicity of a phase II trial with single-agent paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) in previously untreated patients with extensive-stage small cell lung cancer.

Full Text

Duke Authors

Cited Authors

  • Jett, JR; Kirschling, RJ; Jung, SH; Marks, RS

Published Date

  • June 1995

Published In

Volume / Issue

  • 22 / 3 Suppl 6

Start / End Page

  • 75 - 77

PubMed ID

  • 7541157

Pubmed Central ID

  • 7541157

International Standard Serial Number (ISSN)

  • 0093-7754

Language

  • eng

Conference Location

  • United States