Human B cell alloantigens: expression of MB and MT determinants.


Journal Article

Four HLA-DR-homozygous cell lines were examined in detail to compare alpha and beta subunits precipitated by chimpanzee antisera and alloantisera directed against HLA-DR, MB, or MT determinants. For the HLA-DR5-homozygous cell line Sweig, chimpanzee antisera directed against MT2 and against the HLA-DR5 specificity yielded identical patterns. Similar findings for MT and MB vs HLA-DR were obtained for the cell lines LG14 (HLA-DR3-homozygous), PBur (HLA-DR7-homozygous), and Eld (HLA-DRw6-homozygous). Therefore, on some cell lines MT and/or MB specificities appear to be detectable only on the same or electrophoretically identical alpha-beta complexes as HLA-DR determinants.

Full Text

Duke Authors

Cited Authors

  • Markert, ML; Cresswell, P

Published Date

  • May 1, 1982

Published In

Volume / Issue

  • 128 / 5

Start / End Page

  • 2004 - 2008

PubMed ID

  • 6174619

Pubmed Central ID

  • 6174619

International Standard Serial Number (ISSN)

  • 0022-1767


  • eng

Conference Location

  • United States