Fibrinogen content of low-volume cryoprecipitate.

Published

Journal Article

Single-donor cryoprecipitate is the most convenient and reliable source of fibrinogen. A change by the regional Red Cross Blood Service to the production of low-volume cryoprecipitate led the authors to reexamine the fibrinogen content of cryoprecipitate units. The average fibrinogen content of individual low-volume (4 ml) units (n = 23) was 101 +/- 48 mg; in the 10-unit pools (n = 9 pools), content was 89 +/- 13 mg. Both measurements were considerably lower than previously published. By contrast, the mean fibrinogen content of regular-volume (15 ml) cryoprecipitate units (n = 8) was 142 +/- 50 mg. The fibrinogen was stable for at least 4 hours after thawing, and it survived refreezing and thawing.

Full Text

Duke Authors

Cited Authors

  • Hoffman, M; Koepke, JA; Widmann, FK

Published Date

  • July 1, 1987

Published In

Volume / Issue

  • 27 / 4

Start / End Page

  • 356 - 358

PubMed ID

  • 3111036

Pubmed Central ID

  • 3111036

International Standard Serial Number (ISSN)

  • 0041-1132

Digital Object Identifier (DOI)

  • 10.1046/j.1537-2995.1987.27487264748.x

Language

  • eng

Conference Location

  • United States