Increased releasable vascular plasminogen activator and a bleeding diathesis.
Journal Article
A 66-year-old man with metastatic prostatic carcinoma treated with high-dose (5 mg) diethylstilbestrol therapy underwent orchiectomy to allow discontinuation of estrogen. An extensive ecchymosis developed postoperatively in an area covered by elastic dressing tape; subsequently, it was learned that the patient had a recent history of frequent ecchymoses with mild trauma that proceeded to vesiculation. His alpha2-antiplasmin level was 132 percent, fibrin split products 4 micrograms/ml, and fibrinogen 293 mg/dl; routine coagulation results were normal. However, the level of releasable vascular plasminogen activator in a specimen drawn prior to surgery was 3.6 CTA units/ml, the highest value ever reported in this laboratory.
Full Text
Duke Authors
Cited Authors
- Walther, PJ; Gore, M; Pizzo, SV
Published Date
- September 1, 1984
Published In
Volume / Issue
- 77 / 3
Start / End Page
- 566 - 568
PubMed ID
- 6540987
Pubmed Central ID
- 6540987
International Standard Serial Number (ISSN)
- 0002-9343
Digital Object Identifier (DOI)
- 10.1016/0002-9343(84)90123-2
Language
- eng
Conference Location
- United States