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Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat.

Publication ,  Journal Article
Goldstein, LB; Bullman, S
Published in: Restor Neurol Neurosci
1999

Both age and sex can influence recovery after brain injury. To determine the impact of these variables on motor recovery, young (2 month old) and older (5-6 months old) male and female rats were first trained to traverse a narrow elevated beam. Rats then underwent suction-ablation of right sensorimotor cortex or sham operation. Motor recovery was measured by repeated testing on the beam over 3 weeks. Shamoperated rats performed perfectly regardless of age or sex throughout testing. There was no difference in beam-walking scores among the groups of lesioned rats on the first trial 24 hrs. after injury (Kruskal-Wallis H = 0.18, p = 0.98). There was a significant effect of age (two-way ANOVA F1,32 = 29.58, p < 0.0001) but not sex (ANOVA F1,32 = 0.78, p = 0.38) on subsequent recovery. These data show that motor recovery after unilateral injury to the sensorimotor cortex varies with age, but not sex.

Duke Scholars

Published In

Restor Neurol Neurosci

EISSN

1878-3627

Publication Date

1999

Volume

15

Issue

1

Start / End Page

39 / 43

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
 

Citation

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ICMJE
MLA
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Goldstein, L. B., & Bullman, S. (1999). Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat. Restor Neurol Neurosci, 15(1), 39–43.
Goldstein, Larry B., and Sarah Bullman. “Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat.Restor Neurol Neurosci 15, no. 1 (1999): 39–43.
Goldstein, Larry B., and Sarah Bullman. “Age but not sex affects motor recovery after unilateral sensorimotor cortex suction-ablation in the rat.Restor Neurol Neurosci, vol. 15, no. 1, 1999, pp. 39–43.

Published In

Restor Neurol Neurosci

EISSN

1878-3627

Publication Date

1999

Volume

15

Issue

1

Start / End Page

39 / 43

Location

Netherlands

Related Subject Headings

  • Neurology & Neurosurgery
  • 5202 Biological psychology
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences