Focal segmental glomerulosclerosis: a need for caution in live-related renal transplantation.

Journal Article (Journal Article)

Focal segmental glomerulosclerosis (FSGS) has increasingly been recognized to occur in a familial pattern. We have observed the development of biopsy-confirmed FSGS and subsequent end-stage renal disease (ESRD) in one live related kidney donor and ESRD without biopsy in another. Both donors had family members with ESRD secondary to FSGS. Both donors were apparently healthy by routine physical examination, urinalysis, and serum creatinine at the time of evaluation as live related donors. We believe these cases emphasize the need for great caution when evaluating siblings as potential live related donors.

Full Text

Duke Authors

Cited Authors

  • Winn, MP; Alkhunaizi, AM; Bennett, WM; Garber, RL; Howell, DN; Butterly, DW; Conlon, PJ

Published Date

  • May 1999

Published In

Volume / Issue

  • 33 / 5

Start / End Page

  • 970 - 974

PubMed ID

  • 10213658

Electronic International Standard Serial Number (EISSN)

  • 1523-6838

Digital Object Identifier (DOI)

  • 10.1016/s0272-6386(99)70435-x


  • eng

Conference Location

  • United States