Hemodynamic effects of new intra-aortic balloon counterpulsation timing methods in patients: a multicenter evaluation.

Journal Article (Clinical Trial;Journal Article;Multicenter Study)

BACKGROUND: To test whether later intra-aortic balloon pump (IABP) deflation approaching or simultaneous with left ventricular ejection would improve hemodynamics and myocardial efficiency with the use of new balloon deflation methods, 4 IABP timing techniques were evaluated in 43 patients. METHODS AND RESULTS: Later balloon deflation produced significantly greater percentage changes in mean aortic pressure (6% vs 1%), systolic pressure time index (-27% vs -20%), diastolic pressure time index (35% vs 19%), and the systolic pressure-time index/diastolic pressure-time index ratio (97% vs 51%), respectively. However, these changes increased peak systolic pressure (-15% vs -11%). Cardiac output and stroke volume indexes were not significantly altered over the 4 settings. CONCLUSIONS: These data suggest that systemic hemodynamics and myocardial efficiency may be improved by later balloon deflation approaching left ventricular ejection in comparison to conventional IABP timing.

Full Text

Duke Authors

Cited Authors

  • Kern, MJ; Aguirre, FV; Caracciolo, EA; Bach, RG; Donohue, TJ; Lasorda, D; Ohman, EM; Schnitzler, RN; King, DL; Ohley, WJ; Grayzel, J

Published Date

  • June 1999

Published In

Volume / Issue

  • 137 / 6

Start / End Page

  • 1129 - 1136

PubMed ID

  • 10347342

International Standard Serial Number (ISSN)

  • 0002-8703

Digital Object Identifier (DOI)

  • 10.1016/s0002-8703(99)70373-x


  • eng

Conference Location

  • United States