Regulation of mucin genes in chronic inflammatory airway diseases.


Journal Article (Review)

In this review, we summarize work over the past 15 years on mucin gene expression and regulation in the lung, as well as how mucin gene expression is altered in chronic lung diseases. This field owes a great debt to Carol Basbaum for her pioneering work in dissecting signaling pathways regulating mucin gene expression and for her tremendous energy in promoting the importance of understanding the basic pathogenic mechanisms that drive mucus overproduction in cystic fibrosis, chronic obstructive pulmonary disease, and asthma.

Full Text

Cited Authors

  • Voynow, JA; Gendler, SJ; Rose, MC

Published Date

  • June 2006

Published In

Volume / Issue

  • 34 / 6

Start / End Page

  • 661 - 665

PubMed ID

  • 16456183

Pubmed Central ID

  • 16456183

Electronic International Standard Serial Number (EISSN)

  • 1535-4989

International Standard Serial Number (ISSN)

  • 1044-1549

Digital Object Identifier (DOI)

  • 10.1165/rcmb.2006-0035sf


  • eng