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Human G(alpha q): cDNA and tissue distribution.

Publication ,  Journal Article
Chen, B; Leverette, RD; Schwinn, DA; Kwatra, MM
Published in: Biochim Biophys Acta
June 11, 1996

G(alpha q), a member of the Gq family of heterotrimeric G proteins, transduces signals from several G protein-coupled receptors that stimulate membrane phosphoinositide hydrolysis. In order to further define the role of G(alpha q) in the function of G protein-coupled receptors, we have cloned the cDNA encoding human G(alpha q) from a prostate cDNA library. Human G(alpha q) exhibits high homology with its mouse homolog - 94% similarity at the nucleotide level, and 99% similarity at the amino acid level. Northern hybridization data indicate high expression of G(alpha q) mRNA in organs of the human reproductive system including ovary, prostate, and testis.

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Published In

Biochim Biophys Acta

DOI

ISSN

0006-3002

Publication Date

June 11, 1996

Volume

1281

Issue

2

Start / End Page

125 / 128

Location

Netherlands

Related Subject Headings

  • Tissue Distribution
  • Testis
  • Sequence Homology
  • RNA, Messenger
  • Prostate
  • Ovary
  • Molecular Sequence Data
  • Mice
  • Male
  • Macromolecular Substances
 

Citation

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Chen, B., Leverette, R. D., Schwinn, D. A., & Kwatra, M. M. (1996). Human G(alpha q): cDNA and tissue distribution. Biochim Biophys Acta, 1281(2), 125–128. https://doi.org/10.1016/0005-2736(96)00039-9
Chen, B., R. D. Leverette, D. A. Schwinn, and M. M. Kwatra. “Human G(alpha q): cDNA and tissue distribution.Biochim Biophys Acta 1281, no. 2 (June 11, 1996): 125–28. https://doi.org/10.1016/0005-2736(96)00039-9.
Chen B, Leverette RD, Schwinn DA, Kwatra MM. Human G(alpha q): cDNA and tissue distribution. Biochim Biophys Acta. 1996 Jun 11;1281(2):125–8.
Chen, B., et al. “Human G(alpha q): cDNA and tissue distribution.Biochim Biophys Acta, vol. 1281, no. 2, June 1996, pp. 125–28. Pubmed, doi:10.1016/0005-2736(96)00039-9.
Chen B, Leverette RD, Schwinn DA, Kwatra MM. Human G(alpha q): cDNA and tissue distribution. Biochim Biophys Acta. 1996 Jun 11;1281(2):125–128.

Published In

Biochim Biophys Acta

DOI

ISSN

0006-3002

Publication Date

June 11, 1996

Volume

1281

Issue

2

Start / End Page

125 / 128

Location

Netherlands

Related Subject Headings

  • Tissue Distribution
  • Testis
  • Sequence Homology
  • RNA, Messenger
  • Prostate
  • Ovary
  • Molecular Sequence Data
  • Mice
  • Male
  • Macromolecular Substances