Immunobiology of primary intracranial tumors. Part 1: studies of the cellular and humoral general immune competence of brain-tumor patients.

Journal Article (Journal Article)

Cellular and humoral immune parameters were evaluated in a series of brain-tumor patients, 42 with glioblastoma multiforme, 17 with other anaplastic gliomas, and 17 with meningiomas. A degree of anergy was found, which seems in the group as a whole to be proportional to the degree of anaplasia. In addition, serial bimonthyl testing in individual cases revealed further reduction in certain immune responses coincident with clinical decline.

Full Text

Duke Authors

Cited Authors

  • Mahaley, MS; Brooks, WH; Roszman, TL; Bigner, DD; Dudka, L; Richardson, S

Published Date

  • April 1, 1977

Published In

Volume / Issue

  • 46 / 4

Start / End Page

  • 467 - 476

PubMed ID

  • 191575

International Standard Serial Number (ISSN)

  • 0022-3085

Digital Object Identifier (DOI)

  • 10.3171/jns.1977.46.4.0467


  • eng

Conference Location

  • United States