Glial-mesenchymal tropism of in vivo avian sarcoma virus neuro-oncogenesis in rats.

Journal Article (Journal Article)

Intracerebral inoculation of avian sarcoma virus (ASV) in postnatal animals induces gliomas and sarcomas but no neuronal tumors. High titer Bratislava-77 strain ASV was inoculated intracerebrally in fetal F-344 rats between 17 and 20 days of gestation: a time of active neuronal proliferation. Following birth inoculated rats developed gliomas and sarcomas but no neuronal tumors. The results are evidence that the glial-mesenchymal tropism of in vivo ASV neuro-oncogenesis is independent of stage of neurocytodifferentiation at inoculation.

Full Text

Duke Authors

Cited Authors

  • Copeland, DD; Bigner, DD

Published Date

  • January 19, 1978

Published In

Volume / Issue

  • 41 / 1

Start / End Page

  • 23 - 25

PubMed ID

  • 205079

International Standard Serial Number (ISSN)

  • 0001-6322

Digital Object Identifier (DOI)

  • 10.1007/BF00689552


  • eng

Conference Location

  • Germany