Isolated IgA deficiency after chemotherapy for acute myelogenous leukemia in an infant.


Journal Article

IgA deficiency is a relatively common congenital immunodeficiency in children. It can either be asymptomatic or lead to frequent infections, most often of the sinuses and lungs. Intensive chemotherapy for acute leukemia is also profoundly immunosuppressive and can be complicated with life-threatening infections, usually associated with neutropenia and prolonged lymphopenia in the post-bone marrow transplant setting. Isolated, acquired immunoglobulin deficiency that occurs during treatment has been described but is usually transient. In this report, the authors describe a patient with infant acute myelogenous leukemia with acquired, persistent IgA deficiency.

Full Text

Duke Authors

Cited Authors

  • Uram, R; Rosoff, PM

Published Date

  • September 2003

Published In

Volume / Issue

  • 20 / 6

Start / End Page

  • 487 - 492

PubMed ID

  • 14631625

Pubmed Central ID

  • 14631625

International Standard Serial Number (ISSN)

  • 0888-0018


  • eng

Conference Location

  • England