Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase.
Publication
, Journal Article
Rosoff, PM
Published in: J Pediatr
October 1995
A 4-year-old girl known to have peripheral uridine diphosphate-galactose 4-epimerase deficiency was examined for bruising and thrombocytopenia. She had dysplastic peripheral blood and bone marrow changes, with a global platelet function defect. Uridine diphosphate-galactose-4-epimerase participates in a metabolic pathway that provides substrates for posttranslational glycosylation of secreted and membrane glycoproteins, including hematopoietic growth factors and their receptors; there may be a causal relationship between the two disorders.
Duke Scholars
Published In
J Pediatr
DOI
ISSN
0022-3476
Publication Date
October 1995
Volume
127
Issue
4
Start / End Page
605 / 608
Location
United States
Related Subject Headings
- UDPglucose 4-Epimerase
- Receptors, Colony-Stimulating Factor
- Phenotype
- Pediatrics
- Myelodysplastic Syndromes
- Metabolic Diseases
- Membrane Glycoproteins
- Leukopenia
- Humans
- Glycosylation
Citation
APA
Chicago
ICMJE
MLA
NLM
Rosoff, P. M. (1995). Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase. J Pediatr, 127(4), 605–608. https://doi.org/10.1016/s0022-3476(95)70124-9
Rosoff, P. M. “Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase.” J Pediatr 127, no. 4 (October 1995): 605–8. https://doi.org/10.1016/s0022-3476(95)70124-9.
Rosoff PM. Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase. J Pediatr. 1995 Oct;127(4):605–8.
Rosoff, P. M. “Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase.” J Pediatr, vol. 127, no. 4, Oct. 1995, pp. 605–08. Pubmed, doi:10.1016/s0022-3476(95)70124-9.
Rosoff PM. Myelodysplasia and deficiency of uridine diphosphate-galactose 4-epimerase. J Pediatr. 1995 Oct;127(4):605–608.
Published In
J Pediatr
DOI
ISSN
0022-3476
Publication Date
October 1995
Volume
127
Issue
4
Start / End Page
605 / 608
Location
United States
Related Subject Headings
- UDPglucose 4-Epimerase
- Receptors, Colony-Stimulating Factor
- Phenotype
- Pediatrics
- Myelodysplastic Syndromes
- Metabolic Diseases
- Membrane Glycoproteins
- Leukopenia
- Humans
- Glycosylation