Portopulmonary hypertension and the liver transplant candidate.
Publication
, Journal Article
Kuo, PC; Plotkin, JS; Gaine, S; Schroeder, RA; Rustgi, VK; Rubin, LJ; Johnson, LB
Published in: Transplantation
April 27, 1999
The management of the liver transplant (OLT) candidate with portopulmonary hypertension (PPHTN) has dramatically changed in the past 3 years. Careful preoperative evaluation with functional characterization of right ventricular function plays a critical role. The pulmonary vascular response to epoprostenol infusion serves as a deciding factor for OLT candidacy. Careful perioperative attention to avoid right ventricular failure from acutely elevated pulmonary artery pressures or sudden increases in right ventricular preload is a key physiologic tenet of management. With increased surgical expertise, anesthetic sophistication, and availability of epoprostenol, PPHTN is no longer considered an absolute contraindication for OLT.
Duke Scholars
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Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
April 27, 1999
Volume
67
Issue
8
Start / End Page
1087 / 1093
Location
United States
Related Subject Headings
- Surgery
- Postoperative Period
- Liver Transplantation
- Liver Diseases
- Hypertension, Pulmonary
- Hypertension, Portal
- Humans
- 3204 Immunology
- 3202 Clinical sciences
- 11 Medical and Health Sciences
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Chicago
ICMJE
MLA
NLM
Kuo, P. C., Plotkin, J. S., Gaine, S., Schroeder, R. A., Rustgi, V. K., Rubin, L. J., & Johnson, L. B. (1999). Portopulmonary hypertension and the liver transplant candidate. Transplantation, 67(8), 1087–1093. https://doi.org/10.1097/00007890-199904270-00001
Kuo, P. C., J. S. Plotkin, S. Gaine, R. A. Schroeder, V. K. Rustgi, L. J. Rubin, and L. B. Johnson. “Portopulmonary hypertension and the liver transplant candidate.” Transplantation 67, no. 8 (April 27, 1999): 1087–93. https://doi.org/10.1097/00007890-199904270-00001.
Kuo PC, Plotkin JS, Gaine S, Schroeder RA, Rustgi VK, Rubin LJ, et al. Portopulmonary hypertension and the liver transplant candidate. Transplantation. 1999 Apr 27;67(8):1087–93.
Kuo, P. C., et al. “Portopulmonary hypertension and the liver transplant candidate.” Transplantation, vol. 67, no. 8, Apr. 1999, pp. 1087–93. Pubmed, doi:10.1097/00007890-199904270-00001.
Kuo PC, Plotkin JS, Gaine S, Schroeder RA, Rustgi VK, Rubin LJ, Johnson LB. Portopulmonary hypertension and the liver transplant candidate. Transplantation. 1999 Apr 27;67(8):1087–1093.
Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
April 27, 1999
Volume
67
Issue
8
Start / End Page
1087 / 1093
Location
United States
Related Subject Headings
- Surgery
- Postoperative Period
- Liver Transplantation
- Liver Diseases
- Hypertension, Pulmonary
- Hypertension, Portal
- Humans
- 3204 Immunology
- 3202 Clinical sciences
- 11 Medical and Health Sciences