Tracheal intubating conditions after induction with propofol, remifentanil and lignocaine.


Journal Article

We have studied the intubating conditions in 60 ASA I or II patients, after induction of anaesthesia with propofol 2 mg kg-1, allocated to one of the following three groups: group 1, remifentanil 1 microgram kg-1; group 2, remifentanil 1 microgram kg-1 and lignocaine 1 mg kg-1; group 3, remifentanil 2 micrograms kg-1. No neuromuscular blocking agents were administered. Intubating conditions were assessed using a four-point scoring system based on ease of laryngoscopy, jaw relaxation, position of vocal cords, degree of coughing and limb movement. Overall intubating conditions were acceptable in 35% of patients in group 1, 100% of patients in group 2 and 85% of patients in group 3. There was a statistically significant drop in blood pressure after induction in groups 2 and 3, and two patients in each group required ephedrine 6 mg i.v. boluses, as dictated by the intervention criteria (mean arterial pressure fall > 25% from baseline). Similarly, there was a drop in heart rate in groups 2 and 3, but this did not reach statistical or clinical significance, and no patient required atropine.

Full Text

Cited Authors

  • Woods, AW; Grant, S; Harten, J; Noble, JS; Davidson, JA

Published Date

  • November 1998

Published In

Volume / Issue

  • 15 / 6

Start / End Page

  • 714 - 718

PubMed ID

  • 9884858

Pubmed Central ID

  • 9884858

Electronic International Standard Serial Number (EISSN)

  • 1365-2346

International Standard Serial Number (ISSN)

  • 0265-0215

Digital Object Identifier (DOI)

  • 10.1097/00003643-199811000-00014


  • eng