Advances in measuring lifespan in the yeast Saccharomyces cerevisiae.


Journal Article

Much research aimed at discovering the genetic bases of longevity focuses on the budding yeast Saccharomyces cerevisiae. Unfortunately, yeast researchers use a definition of longevity not applied to other species. We propose here a method that makes it possible to estimate for yeast the same measures of longevity calculated for other species. We also show that the conventional method (equating longevity with the number of offspring) is only an approximate measure of true chronological lifespan. Our method will allow results for yeast to be compared more correctly with those for other species.

Full Text

Duke Authors

Cited Authors

  • Minois, N; Frajnt, M; Wilson, C; Vaupel, JW

Published Date

  • January 2005

Published In

Volume / Issue

  • 102 / 2

Start / End Page

  • 402 - 406

PubMed ID

  • 15625107

Pubmed Central ID

  • 15625107

Electronic International Standard Serial Number (EISSN)

  • 1091-6490

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.0408332102


  • eng