An NIH-sponsored user and prescriber preference trial was conducted comparing a new low vision telescope system, the Ocutech Vision Enhancing System (VES) to two conventional Keplarian spectacle telescope systems in a controlled cross-over clinical study performed at four independent low vision clinics. Fifty-five visually impaired individuals, 18-81 years of age, with both previous and no telescope experience, were followed for 8-16 weeks. The experimental and control devices were compared on a series of subject-selected visual tasks using a standardized clinical protocol. Subjects were trained in the use of the systems with standardized clinical methods. The data shows a statistically significant preference of the new design by both patient and clinician with the overriding factors relating to appearance, weight, adjustability and the fit of the frame.