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Flying at the head of the pack: Wnt biology in Drosophila.

Publication ,  Journal Article
Bejsovec, A
Published in: Oncogene
December 2006

The fruitfly, Drosophila melanogaster, has been of central importance in analysing the mechanics of cellular processes. Classic forward genetic screens in the fly have identified many of the genes that define critical cell signaling pathways, for example. Our understanding of the Wnt pathway, in particular, has benefited from the many advantages that the fly offers as a model system. Here, I review the history of these discoveries and highlight the utility of the fly in dissecting the molecular workings of Wnt signal transduction.

Duke Scholars

Published In

Oncogene

DOI

EISSN

1476-5594

ISSN

0950-9232

Publication Date

December 2006

Volume

25

Issue

57

Start / End Page

7442 / 7449

Related Subject Headings

  • Wnt Proteins
  • Signal Transduction
  • Phenotype
  • Oncology & Carcinogenesis
  • Mutation
  • Models, Genetic
  • Models, Biological
  • Drosophila melanogaster
  • Body Patterning
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
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Bejsovec, A. (2006). Flying at the head of the pack: Wnt biology in Drosophila. Oncogene, 25(57), 7442–7449. https://doi.org/10.1038/sj.onc.1210051
Bejsovec, A. “Flying at the head of the pack: Wnt biology in Drosophila.Oncogene 25, no. 57 (December 2006): 7442–49. https://doi.org/10.1038/sj.onc.1210051.
Bejsovec A. Flying at the head of the pack: Wnt biology in Drosophila. Oncogene. 2006 Dec;25(57):7442–9.
Bejsovec, A. “Flying at the head of the pack: Wnt biology in Drosophila.Oncogene, vol. 25, no. 57, Dec. 2006, pp. 7442–49. Epmc, doi:10.1038/sj.onc.1210051.
Bejsovec A. Flying at the head of the pack: Wnt biology in Drosophila. Oncogene. 2006 Dec;25(57):7442–7449.

Published In

Oncogene

DOI

EISSN

1476-5594

ISSN

0950-9232

Publication Date

December 2006

Volume

25

Issue

57

Start / End Page

7442 / 7449

Related Subject Headings

  • Wnt Proteins
  • Signal Transduction
  • Phenotype
  • Oncology & Carcinogenesis
  • Mutation
  • Models, Genetic
  • Models, Biological
  • Drosophila melanogaster
  • Body Patterning
  • Animals