Skip to main content

Capillary network geometry and red cell distribution in hamster cremaster muscle.

Publication ,  Journal Article
Klitzman, B; Johnson, PC
Published in: Am J Physiol
February 1982

Vascular geometry and red cell distribution were examined in 133 capillaries by means of intravital microscopy in the cremaster muscle of the pentobarbital-anesthetized hamster. Significant correlations (P less than 0.01) were found between diameter and flow, length and resistance, red cell transit time and flow, and red cell flux and hematocrit. Most unexpected was the lack of correlation (P greater than 0.2) between flow and resistance, length, or hematocrit. In addition, we analyzed the relation between blood flow and red cell flux at capillary bifurcations. The red blood cells had a slight (7%), but significant (P less than 0.025), tendency to enter the branch having either higher flow, red cell velocity, or pseudoshear rate (velocity/diameter). The net effect of the preferential red cell flow was to reduce mean capillary hematocrit from 13.7% prior to the bifurcation to 13.3% in the two branches. Finally, increasing the oxygen level of the superfusate above the muscle caused vasoconstriction and an increased heterogeneity of capillary red cell flux and hematocrit, decreasing the capacity for oxygen transport to the tissue.

Duke Scholars

Published In

Am J Physiol

DOI

ISSN

0002-9513

Publication Date

February 1982

Volume

242

Issue

2

Start / End Page

H211 / H219

Location

United States

Related Subject Headings

  • Vascular Resistance
  • Regional Blood Flow
  • Muscles
  • Mesocricetus
  • Hematocrit
  • Erythrocyte Indices
  • Erythrocyte Count
  • Cricetinae
  • Cardiovascular System & Hematology
  • Capillaries
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Klitzman, B., & Johnson, P. C. (1982). Capillary network geometry and red cell distribution in hamster cremaster muscle. Am J Physiol, 242(2), H211–H219. https://doi.org/10.1152/ajpheart.1982.242.2.H211
Klitzman, B., and P. C. Johnson. “Capillary network geometry and red cell distribution in hamster cremaster muscle.Am J Physiol 242, no. 2 (February 1982): H211–19. https://doi.org/10.1152/ajpheart.1982.242.2.H211.
Klitzman B, Johnson PC. Capillary network geometry and red cell distribution in hamster cremaster muscle. Am J Physiol. 1982 Feb;242(2):H211–9.
Klitzman, B., and P. C. Johnson. “Capillary network geometry and red cell distribution in hamster cremaster muscle.Am J Physiol, vol. 242, no. 2, Feb. 1982, pp. H211–19. Pubmed, doi:10.1152/ajpheart.1982.242.2.H211.
Klitzman B, Johnson PC. Capillary network geometry and red cell distribution in hamster cremaster muscle. Am J Physiol. 1982 Feb;242(2):H211–H219.

Published In

Am J Physiol

DOI

ISSN

0002-9513

Publication Date

February 1982

Volume

242

Issue

2

Start / End Page

H211 / H219

Location

United States

Related Subject Headings

  • Vascular Resistance
  • Regional Blood Flow
  • Muscles
  • Mesocricetus
  • Hematocrit
  • Erythrocyte Indices
  • Erythrocyte Count
  • Cricetinae
  • Cardiovascular System & Hematology
  • Capillaries