A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.

Published

Journal Article

A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.

Full Text

Duke Authors

Cited Authors

  • Gubbay, J; Collignon, J; Koopman, P; Capel, B; Economou, A; Münsterberg, A; Vivian, N; Goodfellow, P; Lovell-Badge, R

Published Date

  • July 19, 1990

Published In

Volume / Issue

  • 346 / 6281

Start / End Page

  • 245 - 250

PubMed ID

  • 2374589

Pubmed Central ID

  • 2374589

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/346245a0

Language

  • eng

Conference Location

  • England