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A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.

Publication ,  Journal Article
Gubbay, J; Collignon, J; Koopman, P; Capel, B; Economou, A; Münsterberg, A; Vivian, N; Goodfellow, P; Lovell-Badge, R
Published in: Nature
July 19, 1990

A gene mapping to the sex-determining region of the mouse Y chromosome is deleted in a line of XY female mice mutant for Tdy, and is expressed at a stage during male gonadal development consistent with its having a role in testis determination. This gene is a member of a new family of at least five mouse genes, related by an amino-acid motif showing homology to other known or putative DNA-binding domains.

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Published In

Nature

DOI

ISSN

0028-0836

Publication Date

July 19, 1990

Volume

346

Issue

6281

Start / End Page

245 / 250

Location

England

Related Subject Headings

  • Y Chromosome
  • Testis
  • Sex Determination Analysis
  • Sequence Homology, Nucleic Acid
  • Restriction Mapping
  • Nucleic Acid Hybridization
  • Mutation
  • Molecular Sequence Data
  • Mice
  • Male
 

Citation

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Gubbay, J., Collignon, J., Koopman, P., Capel, B., Economou, A., Münsterberg, A., … Lovell-Badge, R. (1990). A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature, 346(6281), 245–250. https://doi.org/10.1038/346245a0
Gubbay, J., J. Collignon, P. Koopman, B. Capel, A. Economou, A. Münsterberg, N. Vivian, P. Goodfellow, and R. Lovell-Badge. “A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.Nature 346, no. 6281 (July 19, 1990): 245–50. https://doi.org/10.1038/346245a0.
Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Münsterberg A, et al. A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature. 1990 Jul 19;346(6281):245–50.
Gubbay, J., et al. “A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes.Nature, vol. 346, no. 6281, July 1990, pp. 245–50. Pubmed, doi:10.1038/346245a0.
Gubbay J, Collignon J, Koopman P, Capel B, Economou A, Münsterberg A, Vivian N, Goodfellow P, Lovell-Badge R. A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature. 1990 Jul 19;346(6281):245–250.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

July 19, 1990

Volume

346

Issue

6281

Start / End Page

245 / 250

Location

England

Related Subject Headings

  • Y Chromosome
  • Testis
  • Sex Determination Analysis
  • Sequence Homology, Nucleic Acid
  • Restriction Mapping
  • Nucleic Acid Hybridization
  • Mutation
  • Molecular Sequence Data
  • Mice
  • Male